Skip to content
Applied Genomics

COSMIC and Galaxy

On eLearning

  1. Go to COSMIC Browser. Search for the IDH1 gene. What is this gene?

  2. What is/are the major mutations found in the gene?

  3. Which tissue shows the highest mutation observation in the IDH1 gene?

  4. Which tissue shows the second-highest mutations observed in the IDH1 gene?

  5. What are some other frequent mutations in the IDH1 gene in cancers?

  6. Why would a specific single amino acid residue be mutated in these tumors?

  7. Create an account on Galaxy: https://usegalaxy.org

  8. Follow the simple tutorial for RNA-seq analysis: https://training.galaxyproject.org/training-material/topics/introduction/tutorials/galaxy-intro-short/tutorial.html

  9. Export your workflow and save.